The division of Molecular Pathology, part of the department of molecular and clinical genomics at Triesta Sciences, houses an expert team of scientists and technologists in our molecular lab in Bangalore.
Molecular pathology is a powerful tool employing state-of-the-art Polymerase Chain Reaction (PCR) technology to understand the molecular landscape of cancer.
This has facilitated the development of diagnostic, prognostic, and predictive biomarkers for clinical oncology. Our commitment to cancer biology is reflected in the comprehensive array of assays being offered targeting various types of solid and liquid cancers. Recent developments in the field of targeted therapies for cancer have increased the demand for accurate, faster, and scalable DNA screening technologies. Key among our PCR tests are those assessing genetic alterations in critical cancer-related genes.
The Epidermal Growth Factor Receptor (EGFR), Neuroblastoma RAS viral oncogene homolog (NRAS), Kirsten RAS (KRAS) and B-Raf proto-oncogene, serine/threonine kinase (BRAF) tests are integral for identifying mutations associated with different cancers, aiding in treatment decision-making, and predicting therapeutic responses.
With cutting-edge technology it is our endeavor to play a pivotal role in advancing personalized medicine and enhancing the quality of care for cancer patients through precise and timely reports.
The department conducts quantitative and qualitative analysis of the Breakpoint Cluster Region-Abelson (BCR-ABL) fusion gene, a crucial marker in chronic myeloid leukemia (CML) and other hematological disorders.
This, combined with PML-RARA testing for acute promyelocytic leukemia, reflects our commitment to addressing hematological malignancies.
Services Offered (by PCR):
- EGFR
- KRAS
- NRAS
- BRAF
- BCR-ABL Qualitative
- BCR-ABL Quantitative
- KMR Chimerism Typing
- KMR Chimerism Tracking
- PIK3CA
- PML-RARA Qualitative
- PML-RARA Quantitative
- AML Panel
- ALL Panel
- MPN Panel
- IDH 1/2
- MGMT
- JAK2
- POLE (COMING SOON-DIGITAL PCR)
USP:
- Validated assays.
- Stringent QC parameters
- Accurate disease diagnosis for effective treatment plans
- Personalized Medicine: analyzing individual genetic variations allows for the customization of treatment strategies, minimizing adverse effects and maximizing therapeutic efficacy.
- Prognostic Insights aiding healthcare professionals predict the course of diseases and make informed decisions about patient management.
- Therapeutic monitoring of molecular changes during treatment for real-time assessment of therapy effectiveness and to facilitate change in treatment plan based on a patient’s evolving molecular profile.
- Early detection of relapse/ genetic predispositions to diseases, enabling proactive interventions and preventive measures for at-risk individuals
Equipment:
- PCR
- RT-PCR
- Digital-PCR
Most Frequently asked Tests
FAQ
What is molecular pathology?
Molecular pathology is a branch of molecular biology that focuses on the study and diagnosis of diseases at the molecular level, examining changes in genes and proteins that might lead to the pathogenesis of a disease.
What tests does the molecular pathology lab offer?
Our lab offers a range of molecular tests, including PCR & DNA sequencing, analysis, to identify genetic mutations and alterations associated with various diseases.
How do I request a test?
You can request a test by submitting a completed test requisition form along with the doctor’s prescription and patient's sample with relevant clinical details. Ensure all necessary information is provided, including clinical history and relevant details.
How are samples collected and transported?
Samples, such as tissue or blood, should be collected using standard procedures and transported to the lab following specific guidelines to maintain sample integrity. (Please contact the customer care for further information)
Turnaround time for test results?
Turnaround time varies based on the complexity of the test. Generally, routine tests have a quicker turnaround, while more complex analyses may take longer.
How are results reported?
Results are reported in a detailed and comprehensive manner, often including interpretation by our expert molecular pathologists.
What quality control measures are in place?
Our lab adheres to stringent quality control measures to ensure accuracy and reliability. Regular equipment maintenance and proficiency testing are integral components of our quality assurance program.
How is patient confidentiality maintained?
We prioritize patient confidentiality and comply with all relevant privacy laws and regulations. Access to patient information is restricted to authorized personnel.
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